Salinomycin sc-253530 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Salinomycin STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA SUPPLIER Company: Santa Cruz Biotechnology, Inc. Address: 2145 Delaware Ave Santa Cruz, CA Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin (Procoxacin) shows selective activity against human cancer stem cells. - Mechanism of Action & Protocol. Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein.

Several recent reports suggested Salinomycin sodium salt. Catalog # 3637. Datasheet / COA / SDS. Antibiotics Small Molecule. Discontinued Product. 3637 has been discontinued. View all Salinomycin is a polyether antibiotic isolated from Streptomyces spp. and a monovalent ionophore for alkali ions with relative K+ selectivity, able thus to interfere Learn more about Salinomycin and get the best prices in the life science marketplace at AG Scientific, Inc. We have over 20 years of experience with Accordingly, we investigated whether salinomycin, a monocarboxylic ionophore, could induce apoptosis in aggressive breast cancer cells or not, as well as its 24 Aug 2019 A few clinical case reports have documented effectiveness of salinomycin in therapy-resistant cancer patients, e.g., a patient with metastatic 25 May 2020 Salinomycin-loaded PLA nanoparticles: drug quantification by GPC and wave voltammetry and biological studies on osteosarcoma cancer stem Unfortunately Salinomycin sodium salt (Cat.

Salinomycin (Procoxacin) shows selective activity against human cancer stem cells. - Mechanism of Action & Protocol.

Get best price and read about company. Salinomycin (SAL), a broad spectrum antibiotic and a coccidiostat has been found to counter tumour resistance and kill cancer stem cells with better efficacy 120 grams Salinomycin sodium. Mechanism of Action: Salinocox® is an Ionophore coccidiostat that forms fat soluble complexes with Sodium and Potassium ions 21 Mar 2018 Sacox® microGranulates, containing salinomycin sodium (SAL-Na), for chickens for fattening and chickens reared for laying have been Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. Salinomycin is not expected to volatilize from dry soil surfaces based upon its estimated vapor pressure. Salinomycin was degraded 50-70% in soil in 7 day aerobic studies, 20-25% was attributed to abiotic reactions and the remaining portion was considered biodegradation.

SALINOMYCIN 62UXS86T64 Overview Structure Names 6: Classification 5: Identifiers 15: Relationships 1: Active Moiety 1: Audit Info References 19: Moieties Abstract Since Salinomycin (Sal) emerged its ability to target breast cancer stem cells in 2009, numerous experiments have been carried out to test Sal’s anticancer effects. What deserve to be mentioned is that Sal can efficiently induce proliferation inhibition, cell death and metastasis suppression against human cancers from different origins both in vivo and in vitro without causing Översättnings-API; Om MyMemory; Logga in 2018-06-20 · Salinomycin is an antibiotic that has recently been introduced as a novel and effective anti-cancer drug. In this study, PLGA nanofibers (NFs) containing salinomycin (Sali) were fabricated by Salinomycin analogs : Mechanistic probes and structure–activity relationships against cancer stem cells.
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Catalog # 3637. Datasheet / COA / SDS. Antibiotics Small Molecule.

At last,Salinomycin(53003 … White to slightly yellow lyophilizated powder. Purity by HPLC: ≥98% ; refer to CoA for more data 2019-11-25 Salinomycin Sodium (syn: Coxistal, Coxistac) is the sodium salt of Salinomycin, a carboxylic polyether ionophore isolated from Streptomyces albus that has been widely used as an agricultural antibiotic to prevent coccidiosis in poultry.
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Purity by HPLC: ≥98% ; refer to CoA for more data 2019-11-25 Salinomycin Sodium (syn: Coxistal, Coxistac) is the sodium salt of Salinomycin, a carboxylic polyether ionophore isolated from Streptomyces albus that has been widely used as an agricultural antibiotic to prevent coccidiosis in poultry. Salinomycin was first isolated in 1974 by the research division of Kaken Chemical Co. in Tokyo Japan. The salinomycin induced anorexia, ataxia, and difficulty rising within 36 hours. The monensin caused anorexia within 36 hours and difficulty rising 72 hours after feeding.

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action of salinomycin. Salinomycin shows cyto- toxic effect by disrupting the balance of sodium and potas- sium ions across the cell membrane and the Visit ChemicalBook To find more Salinomycin(53003-10-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula “To investigate its action, we developed a surrogate salinomycin drug, ironomycin, that was at least 10-fold more potent than salinomycin against CSCs in vitro and Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. Salinomycin (Procoxacin)，一种钾离子载体抗生素，选择性抑制革兰氏阳性菌的生长(gram-positive bacteria)。Salinomycin 是Wnt/β-catenin 信号传导的有效抑制 Vetbiochem India Private Limited - Offering Salinomycin (coccidoline-s), Packaging Type: Bag in Pune, Maharashtra.